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Current treatments for patients with type 2 diabetes are associated with shortcomings (weight gain, hypoglycaemia, and other side effects) that limit the number of patients reaching acceptable therapeutic goals.
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12 Besides, the current available drugs are associated with a number of shortcomings: body weight increase (TZDs, SUs and insulin), hypoglycemia (SUs, repaglinides and insulin) and gastrointestinal side effects (metformin and α-glucosidase inhibitors).
MCD diet is a widely used dietary model of NASH in mice which results in liver injury resembling human NAFLD/NASH and is increasingly used to obtain insights into the pathogenesis of NASH although several shortcomings such as weight loss, lack of insulin resistance and obesity in this model have to be acknowledged [3 5,27].
The regulations proposed Tuesday are intended to compensate for the shortcomings of risk weighting.
Describing the drive to Mr. Shaw, Shakespeare noted a major shortcoming: its 5,000-pound 5,000-pounded a little tiresome to sloweight and stoproved the car's mechanicalittlees.
Inherent safety indices typically suffer from several shortcomings including subjective scaling and weighting of factors, and consideration of limited set of aspects.
The G.O.P.'s signature policy initiative collapsed under the weight of its own shortcomings and contradictions.
The G.O.P.'s signature policy initiative has collapsed under the weight of its own shortcomings and contradictions.
The G.O.P.'s signature policy initiative, directed in the Senate by Mitch McConnell, the Majority Leader, collapsed under the weight of its own shortcomings and contradictions.
By John Cassidy July 28, 2017 The G.O.P.'s signature policy initiative, directed in the Senate by Mitch McConnell, the Majority Leader, collapsed under the weight of its own shortcomings and contradictions.
However, VSAT technology has several shortcomings as asymmetrical transmission rates and weight and cost of equipment [25].
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