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Pearson's R has been chosen as the similarity measure between the expression profiles, in spite of its known shortcoming – measuring the strength of only linear relationships and sensitivity to outliers.
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Earth observation (EO) techniques may provide a solution to overcome this shortcoming by measuring entities of interest at different spatial and temporal scales.
One experimental shortcoming in measuring a protein's half-life with fluorescently labeled tags is the presence of bulky, folded entities at either the N-, or the C-terminus of the investigated polypeptide.
He glances at each team's turnovers and combined total of runs and completions, and also a statistic that has long been derided and disparaged, mocked for its shortcomings in measuring the quarterback's performance.
To overcome the shortcomings of measuring treatment outcome in terms of statistical significance or effect sizes, Jacobson and colleagues [ 14, 20] developed a concept that considers the clinical relevance of treatment change on an individual basis.
To address such shortcomings, we measured protein diffusivity and accumulation within PEG hydrogels with varying PEG molecular weight, concentration and crosslinking mechanism.
For example, one undergraduate expressed concerns about her own shortcomings when measured against the skills and knowledge of postgraduates.
Among these are the night-time expulsion of a maid who has affairs with both the master and mistress of the house; a philandering Damascene housewife measuring the beauties, shortcomings and material benefits of her lovers; a man watching a film about gay lovers on satellite TV, torn between sexual arousal and fear that his sleeping mother will awake.
The shortcomings of the present cortisol measuring methods call for a better procedure in determining extended and long-term exposure to stress.
Only then can system changes be introduced to address any measured shortcomings.
In terms of potential shortcomings, this study measured the adherence to medication by looking at the encashment of prescriptions.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com