In their paper, Karl's team sums up the combined effect of additional land temperature stations, corrected commercial ship temperature data, and corrected ship-to-buoy calibrations.
Of the 90 water samples, six (6.6%), collected in a single cruise-ship, had temperature ranging from 42.4 to 56.6°C.
Vaccine vials were shipped with temperature recording at ≤−50°C on dry ice from the manufacturing facility to sponsor's CRO, which then transported the vials directly to study sites.
These samples were then batch-shipped under temperature-controlled conditions to the University of Navarra's Laboratory of Immunology, for vaccine immune response analysis.
The effects of two common blood sampling methods (serum vs. plasma) and two widely-used serum handling methods (on the clot with ambient temperature shipping, "traditional", vs. centrifuged with cold chain shipping, "protocol") on protein and autoantibody concentrations were examined.
However, an essential feature of the establishment of PDX models should include the standardization of the collection and shipping at room temperature to a central animal facility.
We conclude that all three products meet the target profile described earlier, and would be appropriate for short-term ambient temperature shipping from field clinics to diagnostic laboratories.
In summary, storing whole blood at +4°C for up to two weeks and shipping at room temperature is a convenient method for obtaining HIV-1 gp120 V3 DNA sequence information via testing at a remote laboratory in patients with suppressed viremia.
Storing whole blood at +4°C for up to two weeks and shipping at room temperature is a convenient method for obtaining HIV-1 gp120 V3 sequence information via testing at a remote laboratory in patients with suppressed viremia.
This study shows that prolonged maintenance of whole blood at +4°C for two weeks and shipping at room temperature does not decrease the sensitivity of HIV-1 V3 DNA amplification compared with standard whole blood freezing followed by shipment in dry ice.
