Sentence examples for shifts the expression from inspiring English sources

Add to this research from the University of Surrey published earlier this year: it demonstrated that after just three days of night shifts, the expression of genes was disrupted, meaning that they began to be active at the wrong time of day.

In addition, possible subfunctionalization shifts the expression pattern trends of gene pairs.

Whether through genetic or epigenetic shifts, the expression levels of miRNAs are often altered in many cancers, resulting in abnormal increases or decreases [ 4].

Furthermore, in earlier work, we found that neonatal DZN exposure in vivo immediately shifts the expression of genes required for the generation of neurites (Slotkin and Seidler 2007a) and produces a drop in membrane/total protein prior to the stage at which glia are being generated (Slotkin et al. 2006a).

In the general case, and in order to shift the expression pattern of the genes K symbols up and down we consider a pair of K symbol alphabets: Σ↑ and Σ↓.

Ploidy duplication neither shifted the expression profile of a weakly metastatic cell to that of a highly metastatic one, nor obviously changed the expression levels of signature genes for highly metastatic cells.

However, treatment of wild-type mice with WY14643 and OA shifted the expression of Cyp4F16 to more distal regions, whereas EPA and DHA treatment resulted in significant increased expression in more proximal segments.

Deletion of this element shifted the expression pattern from being neuron-specific to notochord-specific, which is the default pattern observed with the basal promoter plus intron-enhancer combination.

In this case, and in order to shift the expression pattern of the genes K = 2 symbols up and down, we need to consider, for example, the K = 2 symbol alphabets Σ↑ = { V, W} and Σ↓ = { B, C}.

Indeed, shifting the expression of hsa-miR-155 and hsa-miR-503, two miRNAs inversely regulated by TNF-α, towards the level seen in myoblast differentiation, rescued the inhibitory effect of TNF-α on myotube formation.

For example, one "brain-specific" miRNA, miR-124 [ 29], was described in a number of reports and was demonstrated to shift the expression profiles of HeLa cells towards the brain signature [ 30, 31].