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Overall, significant parts of the primary care system are unsustainable financially and clinically, but elsewhere GPs are building new, integrated care systems in the community which hold out the prospect of reducing emergencies, shifting treatment away from hospitals and improving access.
Thus, the hegemony of surgical clipping was broken by aneurysm coiling causing shifting treatment paradigms.
Metronomic administration of chemotherapy leads to a cytostatic action shifting treatment target from cancer cell to tumor angiogenesis.
Of the 71 conventionally staged LAPC patients, 19 (26.8%) had DM on restaging PET/CT, shifting treatment intent from cure to palliation.
Therefore, persistent presence of post-chemotherapeutic CTCs appears to be valuable in the identification of chemotherapy-resistant patients, who could benefit from shifting treatment programme and/or further investigational approaches.
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The results indicated that the shifting treatments gave better results for transformation efficiency than a consistent one in case of kanamycin selection.
They should encourage open discussions with patients on when to expect effects from drugs, and when to shift treatment and health care system.
Most western health care systems have deinstitutionalised care for patients with mental health problems and shifted treatment from secondary care settings into the community [ 12].
More importantly, the evolving gene landscape in NSCLC and the discovery of novel targets have shifted treatment patterns from indiscrimination to personalization.
9 11 In patients treated with a weight-increasing antipsychotic, another possibility would be to shift treatment to a compound with less weight-increasing potential.
Since the G1306E mutant was more sensitive to flecainide than mexiletine in vitro [ 2], we decided to shift treatment to flecainide.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com