This human induced discharge diversion shifted the active delta plain back to the north and changed the northern estuarine system into an active delta plain.
This then reduces Akt/mTOR signalling to shift the active process of myelination to a myelin maintenance state (Cotter et al., 2010).
Understanding the epigenetic landscape of DIPG opens up the opportunity for epigenetic modifiers, which could potentially shift the active genome of this deadly tumor into a silent and regulated state.
We showed previously that removal of these phosphates by mutagenesis of the kinase active site shifted the activation profile to higher Ire1KR32 concentrations [ 8].
Like agonists or inverse agonists, activating or inactivating mutations are capable of shifting the equilibrium toward active and inactive conformations, respectively.
Rapid DES uptake has necessitated shifting the paradigm to active DES-controlled noninferiority study models with most studies using surrogate angiographic measurements to attain adequate statistical power.
(ii) The charge state of the [AuIIITPP]+ cation leads to a negative image charge in the conducting template, which can be utilized to shift the chemically active d orbitals of the Au center to desired energy levels, and thereby, making them active or inactive.
However, bonded lengths much greater than the effective bond length allow for localized debonding and a shifting of the active zone away from cracked areas, allowing more ductile failures.
Omitting the IPV content or shifting from the active to the passive smoking content when women expressed reluctance potentially helped in their retention.
Therefore, to say that a translocation or shifting of the active nucleatic site has occurred in the Maelstrom in the course of its evolution simply cannot be proven at this point without further experimentation or other type of compelling information.
