Sentence examples for shifted expression from inspiring English sources
Also the expression profiling of the Mcph1gt/gt mice did not show a shifted expression of key components of the DNA damage response network, such as BRCA1 and CHK1 that were published to be affected by MCPH1 knockdowns.
The remaining 33% of CAS genes shifted expression during aging in the same direction promoted by CORT, consistent with strengthening of the regulatory actions of CORT in aging.
In addition, more metabolism-related genes were found with shifted expression, especially glycosyl-transferase (P < 0.01, supplemental figure 5 in Additional file 1,).
Of the 217 CAS genes, the majority (67%) shifted expression during aging in the direction opposite that promoted by CORT, consistent with aging-related weakening of or resistance to the regulatory actions of CORT.
As shown in Figure 5, of the 393 genes identified as the chronic CORT-dependent transcriptome, 217 also shifted expression with aging (Supplemental Table 1) and are referred to here as CAS genes.
A shifting pattern follows equation 4. (4) e ij = π i + β j The expression of the ith gene in the jth condition, e ij, is a shifted expression of a base expression π in the ith row shifted by a shifting factor β in the jth column.
After pathogen recognition, the immature DC up-regulate major histocompatibility (MHC) and co-stimulatory molecules, express cytokines, and shift expression of chemokine receptors to direct the DC to the T lymphocyte-rich areas of lymphoid tissue.
Bogart, on the other hand, barely shifts expression.
One of such strategies consists in modulation of AS to shift expression from pro- to antiapoptotic isoforms of several genes.
We defined the genes with the most dramatically shifting expression profiles as 100 genes with the highest standard deviation of logged expression value.
Our analysis supports each of these predictions, as translocated genes tended to shift expression toward their new chromosome neighbors despite inevitable cis-acting regulation of expression.
