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Of the 10 studies identified, AF incidence was only reported in one, the SHIFT trial.
In such sequences, if the participant failed to shift attention on the shift trial, they would make a commission error on the subsequent stop trial, and the preceding shift trial was excluded.
The model has been based on the results of the SHIFT trial [ 9], taking a third party-payer perspective.
Alive patients are subdivided into NYHA classes (I, II, III and IV) taking into consideration the SHIFT trial data.
First level models also included parametric modulators for go trial reaction times (RTs) and shift trial RTs.
The echocardiography substudy of the SHIFT trial showed that ivabradine has a beneficial effect on LV remodelling and function in patients with chronic HF [ 70].
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Half of the shift trials involved colour-to-colour or shape-to-shape (intra-dimensional: ID) shifting and the other half involved colour-to-shape or shape-to-colour (extra-dimensional: ED) shifting.
On the first of the four shift trials (where the newly positioned platform was proximal to the rat's starting position), female rats showed the previously found tendency to adopt a perceptual style escape directly in clear contrast to saline-treated males.
A significant late cue instruction effect can also be noted on detection rates which are 8% higher on stay trials than on shift trials (Duncan test, p = 0.044).
In spite of this, there is a statistically significant early cue instruction effect on reaction times which are 38 ms longer on shift trials than on stay trials (Duncan test, p = 0.041).
These studies predict in particular reaction times trends between Stay and Shift trials opposite to those described here, suggesting that the observations provided therein do not apply to our experimental context.
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Justyna Jupowicz-Kozak
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