Sentence examples for shift the fate of from inspiring English sources

Other therapeutic approaches include promoting protein folding to shift the fate of mutant heterotrimers and alleviate intracellular and extracellular insults.

Thus TAF7L expression appears to shift the fate of a stem cell towards brown adipose tissue, potentially at the expense of skeletal muscle, as both cell types develop from the same group of stem cells.

Based upon the promising proof-of-principle experiment in C. elegans, it is possible that we are not simply shifting the fate of mutant heterotrimers but also qualitatively altering them to functionally rescue the extracellular effect.

Taken together, these results suggest TIMP-1 increases the expression of anti-apoptotic proteins in neurons challenged with cytotoxic stimuli and also inhibits the expression of pro-apoptotic proteins, which protects neurons from mPTP opening and shifts the fate of neurons from apoptosis toward pro-survival pathways.

Impaired PPARγ signaling shifts the fate of MSC toward the osteoblast lineage.

These data suggest that Cdx transcription factors can shift the cell fates of glandular cells and suggests they may also be involved in the progression of Barrett's esophagus.

Tonight, the Jets (9-4) will try to do much better, with a playoff berth on the line for both teams and a subtle shift in the fate of road warriors in place.

The possible shift in the fate of progeny and the resulting alterations in the relative cell numbers in the cerebral cortex following a maternal inflammatory response shown here will require further investigation to determine the long-term consequences of inflammation on the development of neuronal circuitry and behaviour.

TAG accumulation can result from a shift in the fate of fatty-acyl-CoA toward esterification with a corresponding decrease in oxidative rate, or from an imbalance between cellular fatty acid uptake and oxidation, with a more important increase in uptake than in oxidation, in the absence of any absolute decrease in lipid oxidation.

Finally, all of the toxicants shifted the transmitter fate of the cells away from the cholinergic phenotype and toward the catecholaminergic phenotype.

Moreover, intensification of imprinting in modern rodents seems to have shifted the evolutionary fate of imprinted genes towards strong purifying selection.