Your English writing platform
Discover LudwigSuggestions(1)
Similar(60)
The proposal to shift rates in this way was first made in 2008.
MMR deficiency leads to a high mutation rate in simple sequence repeats, and especially in mononucleotide repeats [ 26], and it has been shown experimentally that in mycobacteria, the frame-shift rate in mononucleotide repeats is particularly high [ 23].
The shift rate for superposition is in the same range, but slightly higher in nanocomposites.
The first assumption was that the frame-shift mutation rate in a C6 repeat in Mycobacteria is about 3*107 [ 23].
First, we estimated the frame-shift mutation rate in mononucleotide repeats in coding regions of the M. tuberculosis genome.
We used the same method to determine the estimated frame-shift mutation rate in the randomized genomes.
The factor 3*10-7 is based on the estimated frame-shift mutation rate in C6 repeats of Mycobacteria [ 23].
This estimate was based on published measurements of the frame-shift mutation rate in mononucleotide repeats in Mycobacteria and other bacteria (see Methods).
A further assumption was that the frame-shift mutation rate in mononucleotide 'repeats' of length two and three (for example, CC and CCC) is negligible, and that only repeats of length four and longer have a significant frame-shift mutation rate.
The second assumption was that in bacteria, the frame-shift mutation rate in repeats of C and G is about five times higher than in repeats of A and T of the same length [ 42].
Robert Lynch, president of Americans for the Arts, a nonprofit organization in Washington, said that shifting rates reflected, in part, an expanded definition of the arts and a wider variety of ways to participate.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com