The splicing of these mRNAs results in the appearance of an activation domain (yeast and mammals) or a nuclear localization signal (rice) through frame-shift of their translation products [ 6, 12- 15].
In the 1990s, Chinese scholars began to write and publish professional textbooks, while shifting the focus of translation to classic works of the 1950s, such as the first five books of the Modern Anthropological Classics series published by Huaxia Publishing House in 2002 (Malinowski, 2002).
We aim to facilitate a paradigm shift, enabling translation of findings under physiological conditions in vitro to disease pathology and the design of novel therapeutics.
These strains are C5 deficient because of frame shift deletion and early termination of translation [ 75].
Because of the nature of the mutation, causing a frame shift and a premature termination of translation, congenital lactase deficiency was confirmed and intestinal biopsies were unnecessary.
Inhibition of translation may shift cell metabolism to a physiological state that favours maintenance and repair and this may lead to extension of lifespan.
None of the cDNA clones encodes the FU protein that has previously been described [ 8]. 1HFU lacks the sequence encoded by exon 8, which results in a frame shift and a premature termination of translation.
We suspect that the lack of GFP protein production results from unknown alternative translational start sites, which could shift gfp translation out of frame.
This results in a frame-shift and a premature termination of translation.
