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Adequate LNs resection was neither associated with shift of stage from II to III (P = 0.3) nor with the changes from stage IIIa to IIIc (P = 0.9).
As the stage-specific survival increases in patients with colon cancer were weaker than the overall increase, a shift of stage distribution towards earlier stages at diagnosis may partially account for the observed increase in survival.
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Part of this can be explained by the fact that the different interpretations of ITDs in node-negative CRC patients in the subsequent editions of staging systems throughout the past years resulted in a shift of certain stage II patients to stage III.
For wheat, a forward shift of phenological stages was also found for all regions (Additional file 2: Suppl Material 9, Fig. 4).
*Models vary in terms of the shift in distribution of stage at diagnosis attributed to increase in mammography rates.
The main benefit of increased mammography rates is in shifting the distribution of stage at diagnosis, and therefore the subsequent survival probabilities, among those women diagnosed with breast cancer [ 19].
Further research is needed to assess the implications of stage shift on mortality reduction.
Model I is least optimistic in terms of the amount of stage shift produced: model IV is most optimistic.
Analysis of the yearly data similarly showed a parallel increase in presentations with both T1 T2 and T3 T4 disease between 2000 and 2010, supporting the notion of a lack of stage shift between these two periods.
Large-scale early detection of breast cancer leads to an increase in newly diagnosed cases and a shift of breast cancer stages towards higher proportions of less severe tumours.
The frequency shifts of all-stage in the FBAR biosensor can be measured, and thus, the according biochemical reaction process can be judged.
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CEO of Professional Science Editing for Scientists @ prosciediting.com