"This is a cultural shift of enormous significance," said Arthur Miller, a law professor at Harvard.
It will represent a paradigm shift of great significance, securing the political will necessary to stamp out the practice.
In a shift of much significance, per capita water use -- on the rise in most of the rest of the world -- is now declining in the United States.
Even so, all three dismissed the political chatter as a fixation of the media and looked instead to emphasize the official purpose of the day trip: a shift of great significance in America's overtime pay structure.
If normal service appeared to have been resumed, a shift of the greatest significance in scenery backstage has laced this forthcoming season with a glorious unpredictability at the top end of the table.
That Ireland game was the start of a real shift in the significance of the fixture.
The conversation with Mr. Qurban, and at least a dozen others like it with Muslims in Luton, captured a shift of potentially far-reaching significance.
The shift of emphasis has deeper significance, suggesting one theory that Barzun finds almost universally applicable -- a point of view that a historian of ideas might label aristocratic pessimism.
We consider a number of different situations that can manifest themselves in hydrologic time series, including the dependence of the results on the magnitude of the shift, significance level, sample size and location of the change point within the series.
In the left language areas, the focus of significance was shifted toward TP but still comprised middle TC.
All probesets that display a shift with a significance value of p < 0.01 were selected for further analysis.
