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One alternate transcript involved the deletion of exon 10 (117bp.Gly1000_Gly1038del3del, p.Gly1000_Gly1038del), and the other included a 31bp deletion in exon 10 (p.Gly1028fs*33113del, p.Gly1028fs*3) that resulted in a shift of reading frame and a premature termination codon (PTC) (at codon 1030).
However, immediately after the first cysteine in the Ig2 domain encoding exon, a nucleotide deletion results in a shift of reading frame.
Similar(58)
The analyses of the linkage between hypermutability and mutations observed in mucA, lasR and mexZ included only nonsynonymous mutations, which are expected to cause partial or complete loss of function in the genes by generation of premature stop codons, shifts of reading frames or deletions/insertions in the coding sequence.
However, insertions/deletions (indels) between duplicated genes, which may cause shifts of reading frame [ 32], have greater effects on the divergence in protein secondary structures [ 33- 35].
Cloning of 2 transposons having a relatively low divergence rate indicates the rapid accumulation of incapacitating mutations, such as insertions or deletions, shifts of reading frames and premature stop codons.
Finally, we examine the dynamics of intron gain/loss in the context of reading phase shifts.
In hindsight, we made too many mistakes in terms of reading the wind-shift.
Free from the hard work of reading a gear-shift knob.
Thus, the gaze must shift swiftly and accurately during the process of reading.
I read Night Shift in the very early 90s: no internet, no way of reading about authorial motivation or whatever.
Both RPM and RPKM shifted the distribution of reads markedly, which influenced the final results by dramatically reducing their overall expression values.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com