The use of a closed-loop allostatic, acoustic stimulation neurotechnology in a series of athletes with PPCS was associated with improvements in clinical symptoms and autonomic cardiovascular regulation, potentially mediated by shifting of brain electrical activity patterns in the direction of greater hemispheric symmetry and reduction of high-frequency amplitudes.
One of the earliest reports of brain MRI findings in acute Sydenham chorea demonstrated increased signal intensity in the caudate nucleus, a component of the basal ganglia, with associated edema and shifting of brain matter.
This shifting of brain glucose thresholds to higher levels (i.e., it takes a lower plasma glucose to activate symptom responses) is dangerous because it masks most of the mild hypoglycemia episodes until blood glucose decreases to ≤50 mg/dl.
Common findings on both CT and MRI in any type of brain herniation are displacement of brain parenchyma, midline shift and ventricular compression.
Hence, there may be a systematic error due to intraoperative shift of the brain prior to obtaining the localizing CT.
New Figures 2 and 3 (old Figure 2) describe the DNA content shift of whole brain nuclei stained for propidium iodide, while (now) Figure 4 demonstrates that upon immunolabeling of these nuclei for a highly validated neuronal marker, NeuN, the right shifted nuclei are largely neurons.
Also, an ECT-induced shift of the brains inhibitory (GABA) versus excitatory (glutamate) potency has been suggested to explain ST increase during the course [ 22, 33].
Increased ICP causes shift and deformation of brain tissue, complicating the injury further and rapidly proving fatal if unchecked.
If these initial observations are confirmed with more patients, we can foresee emerging of noninvasive monitoring technology for brain damage with the potential to lead to paradigm shift in treatment of brain stroke and traumatic brain damage.
Local mass effect: shifting of the brain structures owing to the TLN nidus.
