Exact(4)
Hybridisation, even between closely related species [10], frequently brings about an abrupt shift in the regulatory networks, as a consequence of the interaction between distinct parental gene hierarchies [11].
Although increased oversight of genetic tests has been recommended ubiquitously [ 14, 57, 84, 87- 91], there was no dramatic shift in the regulatory culture of genetic tests until 2010, when Pathway Genomics Corporation (PGC) announced plans to sell genetic test kits at Walgreens Pharmacy.
The observation that there are considerably more different sequence signatures present in the earliest DPAs of ovule development (0 DPA to 2 DPA) than in later periods may indicate that there is a shift in the regulatory landscape after 2DPA with fewer small RNAs present but in higher numbers later on.
The introduction of CG into the National Health Service can be seen as a fundamental shift in the regulatory relationship between the state and medical professionals [ 29], while at the organizational level it can be considered a process that involves a move towards "encoded knowledge" through the use of "soft bureaucracy" [ 30].
Similar(56)
Major shifts in the regulatory environment has been found to serve as punctuated equilibria [25].
We have demonstrated massive convergent shifts in the SP1 regulatory system in birds and eutherian mammals, including global cis-regulatory conversions across hundreds of promoters and multiple convergent replacements in paralogs SP3 and SP4.
In our work we study how dynamic shifts in the transcriptional regulatory network during this developmental pathway are regulated and how transcription factors control the activation of hematopoietic genes.
On the other hand, the shift of the regulatory module in rhesus monkey Wnt5a compared to human Wnt5b, prompted us to further investigate expression data of Wnt5 genes in embryonic stem cells and several adult tissues of Macaque.
First, the shift in regulatory molecules, from the classic CD28-CD80/CD86 patowalternateernate immunoreceptors, changes the cellular context in which T-cell stimulation is facilitated.
Then, the increase in PSY activity shifts probably the regulatory step from PSY to a later enzyme (Shewmaker et al. 1999; Fraser et al. 2002).
They also support a model in which strong cross-bridges shift the regulatory equilibrium from a TnI actin Tm interaction to a TnC TnI interaction that likely enhances calcium binding by TnC.
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