I would therefore urge the authors to shift the emphasis in the initial part of the paper towards what their technique and dataset tells us about the dynamics of connectivity in these brain regions, as opposed to being so heavily focused on the methodology.
Reviewer #2: I would therefore urge the authors to shift the emphasis in the initial part of the paper towards what their technique and dataset tells us about the dynamics of connectivity in these brain regions, as opposed to being so heavily focused on the methodology.
To rationalize the changes in the solution state as crystallization proceeds, we consider values of Δ δ iclassic= δ istart− δ ieq DMSO), representing the difference in each chemical shift between the initial maximally supersaturated solution and the final equilibrium saturated solution.
Siegel et al., for instance, have run a small-scale comparison between online and offline groups, showing that the process of finding a consensus is resolved with a significantly bigger shift from the initial members' opinion in the online case rather than the offline one [42].
This behavior suggests a shift, from crystallite migration in the initial stages of heat treatment, to atomic migration in the latter stages.
However, the initial shift in the adaptive landscape into colder climates appears to be a precondition, and may not be directly related to increased diversification rates.
This phenomenon can be explained in terms of the characteristics of inflammation induced with ligature placement, an acute and short-termed inflammation that resulted in the initial shift of equilibrium from bacterial endotoxin, that is, LPS, to host response.
As the mean grain size increases, a horizontal shift in the peaks with respect to the initial grain size is observed.
The reversal potential of the current (Fig. 4B) shifted from approximately -24 mV in the initial state to about -4 mV in the activated state, consistent with the activation of a non-selective cationic conductance permeable to both Na+ and K+.
This shift in x removes the initial condition term.
