However, Bdph at 300 μM significantly enhanced the antagonistic effect of 4-AP (5 mM) and rightward shifted the curve in the combination.
Similarly, multi-metric elastic net analyses did not show strong evidence for a specific effect with phase shift in combination with the other parameters but provided additional evidence for nonsignificant small effects of all shiftwork factors combined.
Reduced lifespan may result from an faster age-dependent increase in mortality rate (an increase in the slope of the mortality trajectory), from an increased risk of death at all ages (a shift in the mortality trajectory), or a combination of the two.
Although immigration may also cause an outward shift in labor demand, the combination of increased labor supply and demand due to immigration likely yields excess supply in the labor market.
Finally, we announce a paradigm shift in RILIS operation – the combination of a machine protection and a monitoring and control system has enabled on-call operation of the laser ion source for selected beams in 2014 and has become the standard mode of operation in 2015.
Temperature is an important driver of the trophodynamics of the North Sea ecosystem and a recent shift in temperature, in combination with overfishing, has established a new ecosystem dynamic regime through a series of internal mechanisms [ 1].
However, in the combination treatment, there was a striking shift in the dose response curve when compared to VN/66-1 VN/66-1
Over the past 15 years, there has been an undeniable shift in the British public's attitudes to art, due to a combination of factors.
As shown in Figure 2, comparisons of dose response curves (cell viability) of LCC6 and LCC6Her2 cells treated with 267 and Dt alone and in combination showed that when used in combination there was a shift in the dose-response curves to the left when the doses plotted for the combination are defined by the most active agent in the combination (Dt).
The results showed a left-shift in the dose-response curves of the combination treatments compared to the corresponding curves with either Gem or Cp alone in all tested cancer cells.
