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However, we are interested in the event of founder domain formation per se, which we expect to be characterized by a shift in sequence space, where a substantial proportion of amino acid sites has changed.
This striking shift in sequence similarity from similarity among orthologues across specimens (grey) to similarity/identity among paralogues within specimens (white) is also reflected in our sequence section-specific phylogenetic analyses using ML.
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We are, however, observing a critical shift in sequencing technology where larger datasets with longer reads and higher coverage become available.
Importantly, there was an inverse relationship between the ahead and behind lengths decoded from the simulated data, which reproduces the apparent shift in sequences ahead or behind the animal observed in experimental data (cf. Figure 4c of Gupta et al. (2012)).
DUAL-CLUTCH TRANSMISSION: This automated manual gearbox changes ratios without interrupting power to the wheels; gears must be shifted in sequence.
Small shifts in sequence can have a large effect on siRNA potency.
The likely cause of this difference in promoter sequence is a long shift in promoter sequence alignment.
As evidenced previously [ 4], incorrect annotation of the ORF is caused by a frame shift in the sequence presumably due to a missing base in the genome sequencing.
which is reciprocal to (5.21) and differs from (5.19) only by the shift in the sequence.
This shift in the sequence positions reduces genome similarities when they are calculated based on global alignment.
First, the presence of a stop codon was analyzed, since there was the possibility of a phase shift in the sequence.
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