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Specifically, betel/areca consumption among Asia-born populations is suspected to be a primary driver of the observed geographical shift in incidence from urban cores to suburban neighbourhoods.
Finally, there was no evidence in the BRFS data that the shift in incidence trend that occurred among white males beginning in 1999 was preceded by a shift in BMI in this population.
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Mathematical models offer powerful tools for understanding geographic shifts in incidence as climate changes.
The initial baseline equilibrium does not include any external funding, and there are no shifts in incidence of either disease.
However, during the past decade the incidence has again shown an increasing trend in many developed countries with a shift in the incidence towards older age groups [1].
In two large cohorts of ICU patients, we found a shift in the incidence of dysnatremias.
In two large Dutch cohorts, we observed a marked shift in the incidence of dysnatremia from hyponatremia to hypernatremia over two decades.
Based on our impression that hypernatremia has nowadays become more prevalent than hyponatremia in the ICU, we hypothesized that a shift in the incidence of hyponatremia and hypernatremia occurred during the past two decades.
In this large retrospective dual-center study, we observed a consistent and marked shift in the incidence of dysnatremia from hyponatremia to hypernatremia over a two-decade observation period.
Hence any shift in disease incidence into older age-groups is also likely to give rise to shift in clinical presentation of severe malaria disease.
This increase included a seasonal shift in HFRS incidence from one epidemic peak in the end of the year to dual epidemic peaks in the beginning and in the end of the year.
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