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But Whitaker is usually known for his gentleness: he has a silent, vivid watchfulness, broken by a sudden smile or a slight shift in expression as a thought crosses his mind.
Ca2+ imaging showed that differentiation from BrdU+/TuJ1− to BrdU−/TuJ1+ cells was accompanied by a shift in expression of functional receptors for neurotransmitters from cholinergic and purinergic to predominantly GABAergic and glutamatergic.
Further gene expression profiling by quantitative real-time PCR at 16 72 h revealed a distinct shift in expression of the fatty acid/triacylglyceride biosynthesis and β-oxidation pathways, when cells transitioned from log-phase into early-stationary and stationary phase.
Conclusions: The reprogramming of gene expression in livers with a postsinusoidal hindrance of blood flow results from declining access of the hepatocytes to intrasinusoidal signal-transduction molecules and suggest that the impaired biotransformation that accompanies right ventricular failure is caused by a central-to-portal shift in expression of the corresponding enzymes.
These transgenic mice (TgAQP1+/+) showed increase in fiber cell membrane water permeability without any morphological, anatomical or physiological defects compared to the wild type indicating that the main purpose of the shift in expression from AQP1 to AQP0 may not be to lessen the membrane water permeability.
Christie, meanwhile, managed to speak volumes with a single reflexive shift in expression.
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Kiarostami's use of subtle shifts in expression to celebrate life is mesmerising.
Ms. Linney spends much of her performance stock-still, hands clasped, telegraphing a spectrum of feelings with small, amazingly articulate shifts in expression and posture.
Think of Enid Coleslaw, the snarky teenage anti-heroine of "Ghost World," and her big, black nerdy-hip glasses; they cover most of her face, but they can't conceal the tiny shifts in expression that loudly telegraph her mood.
Both may exhibit shifts in expression of epithelial and mesenchymal markers, which may show dynamic changes during cancer progression.
It is also possible, though we believe less likely, that gains and losses of transgene copies or other factors such as genomic instability may be involved in the dynamic and reversible shifts in expression level we have observed.
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