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Although the shift in concept is clear, and the technology is coming along, there is still a long way until biomolecular simulations, the generation of conformational ensembles, would become a routine.
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However, it also may provide tools for other explanations, for instance of the way in which shifts in concepts of scientific rationality and divisions of cognitive labor across communities may track shifts in reward structures.
The word associations were a helpful exploratory tool and revealed intriguing shifts in concepts used by students in their explanations of phenotypic variation.
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The aforementioned changes point to the fact that a paradigmatic shift in our concept of the American dream is underway.
I believe that the "gizmos" are not themselves to blame for unnecessary rescues — the problem is that the devices have engendered a radical shift in the concept of adventure.
Other than the impact of an economic downturn and clear disequilibria in the supply and demand of the various workforces, a paradigm shift in the concept of employment is affecting the way jobs and careers are perceived.
The shift in the concept of Jabba the Hutt from a furry creature to a slug and from a puppet to CGI represent two of the more glaring changes to the character in the concept and creation process.
Still, a ruling in favor of for-profit religious freedom would signal a pretty major shift in the concept of corporate personhood, dramatically expanding on the 2010 Citizens United v. Federal Election Commission ruling that granted companies full rights to freedom of speech, including the right to make campaign donations.
Taken together, these observations have led to a paradigm shift in the concept of T cell memory in skin, and suggest that host defense to pathogens previously encountered through skin is mediated to a significant degree by tissue TRM.
Although these initial results were disappointing, evidence of the efficacy of bevacizumab came shortly thereafter, leading to an eventual paradigm shift in the concept of antiangiogenic therapy.
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