Sentence examples for shift an equilibrium from inspiring English sources

Thus, environmental stimuli appear to shift an equilibrium between the kinase-on and kinase-off states in chemoreceptor patches, thereby allosterically modulating net kinase activity and flagellar rotation.

Noting the wide spectrum of potencies of different cofactors at saturation, Pcof, we propose a simple model in which cofactors bound in the ATP pocket shift an equilibrium between an inactive and an active conformation of Ire1.

The results are consistent with the idea that inositol hexaphosphate shifts an equilibrium between high- and low-affinity forms of the protein.

The well-known anomalous codeposition became less significant with increasing electrolyte temperature, and the deposition eventually shifted to an equilibrium mode in which the electrolyte composition was approximately equal to the deposited one at 353 K.

A ligand can shift a protein's folding/unfolding equilibrium by binding with higher affinity to the native state.

When ligand binds, PKA-C undergoes linear chemical shift changes between the apo and closed forms of the enzyme, indicating that ligand binding shifts a preexisting conformational equilibrium from the open and closed state in the fast exchange regime on the chemical shift time scale.

Substrates bind between the two domains and shift the equilibrium towards a closed state, a process often referred to as a Venus fy-trap mechanism [13].

Thus, the pathogenic single point mutations may shift the equilibrium to a distinct conformational state, leading to a different aggregation pathway, which is demonstrated for WT and G53A TTR in this report.

Preliminary NMR experiments indicate that phosphorylated hSH3C maintains its fold (data not shown), however lipid binding might shift this equilibrium towards an unfolded conformation.

The phenomenon has been interpreted as the effect of the chiral polarization in a mirror symmetry breaking scenario13, 19, but also that macroscopic hydrodynamic forces could shift the equilibrium of a racemic mixture of J-aggregates, driving a redistribution of chiral aggregates favored by the stirring32.

In order to detect genetic signatures of recent population bottlenecks in the nSSR dataset, we applied two tests implemented in BOTTLENECK 1.2.02 [ 55]: (i) Wilcoxon's sign-rank test for heterozygote excess; and (ii) the 'mode-shift test' for detecting a shifted, rather than an equilibrium, L-shaped distribution of alleles.