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The hMSCs was chosen to form cell sheet matrix due to its stabilization ability for new-formed blood vessels as a pericyte and the osteogenic differentiation potential.
In additional, more experiments need to be performed to investigate the mechanism of vascularization of HUVEC/hMSC cell sheet to fully understand the roles of cell sheet matrix components and for further improvement of vascularization.
In addition, if additives could be further introduced into the rebar graphene sheet matrix during the annealing process, such as nitrogen and borane doping, the doped hybrid material could have potential applications in fuel cells and lithium batteries.
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In a cross-ply laminate, where alternating ply groups are separated by aluminium sheets, matrix cracking and delamination failures are suppressed by the occurrence of plastic deformation.
The latter compose a striated-sheet matrix surrounding the collagen fibrils [5].
In such a model, the fibers correspond to the collagen fibers and the matrix corresponds to the striated-sheet matrix of non-collagenous proteins.
Because this gap between collagen fibers is composed of striated-sheet matrix, larger gaps sizes at the apex agree with the smaller shear moduli we found at that location of the cochlea.
The central core of the wild-type TM is characterised by the presence of radially-oriented collagen fibrils embedded within a distinctive striated-sheet matrix structure (Fig. 6E).
Furthermore, mutations involving cysteine residues in the fourth vWF type D repeat of the ZA domain have little, if any, effect on the structure of the striated-sheet matrix, whilst mutations in the ZP domain only impinge upon the integrity of the striated-sheet matrix within the medial region of the TM, and not in the more lateral regions.
These properties have led to the suggestion that Tecta and Tectb form filaments (either hetero- or homomeric) through their ZP domains that are cross-bridged by the ZA domains of Tecta to form the striated-sheet matrix (2).
Tecta and Tectb are both required for formation of the striated-sheet matrix (22, 23), a laminated matrix within which the collagen fibrils of the TM are imbedded (24).
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