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The design of the SHARP trial balanced rigorous clinical trial methodology with principles of TCM.
This paper describes the design of the Stop Hypertension with the Acupuncture Research Program (SHARP) trial, a pilot randomized clinical trial designed to gather preliminary data regarding the efficacy of traditional Chinese medicine (TCM -based acupuncTCM -basedontrol of essentiacupuncturesion.
These results were similar to those obtained in the SHARP trial (Llovet et al, 2008).
Three patients were investigated in part during the phase III SHARP trial [ 6].
Details of the design of the SHARP trial and its main results have been reported previously [ 15, 16].
Its efficacy and safety in HCC patients were demonstrated by the SHARP trial in western patients [ 70, 71].
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Those other pieces can't be "essays" (looser meaning) because they're strong, and able to endure the sharpest "trial" (stricter meaning).
"I hold," he writes, "none of these ancient short manner of writings, nor Montaigne's, nor such of this latter time to be rightly termed essays, for though they be short, yet they are strong, and able to endure the sharpest trial: but mine are essays, who am but newly bound prentice".**** From this initial mushroom ring of essayists that crops up on the island around 1600, an infestation spreads.
As designed, the SHARP-P trial targeted the detection of intervention mean relative effects of 20% differences on domain specific tests in marginal comparisons, which was equivalent to an average of 0.64 standard deviations across domains.
The Study of Heart and Renal Protection (SHARP) randomized trial prospectively collected information on kidney disease progression, serious adverse events and hospital care use in a cohort of patients with moderate-to-severe CKD.
By Avi Zenilman May 26 , 2009The White House's official background briefing for Judge Sonia Sotomayor, Barack Obama's nominee for the Supreme Court, describes her as a "A Sharp and Fearless Trial Judge" and points to her 1995 injunction that ended the baseball strike.
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