Sentence examples for sharp activation from inspiring English sources

We propose that when EGF exceeds a critical concentration threshold ubiquitination is triggered, which leads to a sharp activation of the major degradative route, NCE.

Addition of TNFα (100 ng/ml) to MEFs induced a rapid and sharp activation of the SAPK followed by a quick down-regulation.

The sharp activation of oxidation and phosphorylation in the lamprey liver mitochondria is followed by spawning and death of the animal in the end of spring—in the beginning of summer.

Thus, the sharp activation of NCE above a certain ligand threshold (while CME nevertheless persists) might regulate the net signalling output, in response to increasing EGF concentrations, in a nonlinear fashion.

The slow and sharp electrode activation with increasing cathodic potential is shown to be related to the removal of this layer.

It is concluded that zinc deposition and dissolution involve at least four adsorbates, do not occur only by series reactions and particularly imply a slow and sharp electrode activation with increasing overpotential.

Positive and negative feedback loops within proximal TCR signaling generate a sharp digital activation filter that is necessary for efficient discrimination of antigenic ligands (Altan-Bonnet and Germain, 2005; Das et al., 2009).

In the case of dynamic-clamp conductance injection we found that the I V curve was best fitted by a non-linear integrate-and-fire model that comprised two exponential components: the sharp exponential activation associated with the spike-generating sodium current is preceded by a slow inward rectification that is also very close to exponential.

In other words, all the selected cases correspond to visually sharp seismicity activations (at rates at least few times higher than the background).

These effects were accompanied by a sharp increase in activation of signal transducer and activator of transcription 3 (STAT3).

For example, the hb shadow enhancer helps produce a sharp boundary of activation by the Bicoid gradient, while its snail (sna) counterpart helps ensure reliable activation under stressful conditions such as high temperatures (Perry et al., 2010, 2011).