A successful bunt would share the same classification.
Consequently, tumors of endometrial and stromal cells share the same classification (sub-coelomic ductal).
Meanwhile, if a hit does not share the same classification as the seed entry, it is a false-positive if its score is equal or above the cutoff, otherwise it is a true-negative.
We observed that only 6 out of 18 unpredicted essential metabolic genes share the same classification with truly predicted ones (see Additional File 2) and may have local interactions within the essential complexes they belong to.
Regarding the definitions of these distances, we defined "cognate" distances as distances between datasets that shared the same classification variable (for example, the root-specific dataset and root EB2 dataset), and "noncognate" distances as distances between datasets that did not share the classification variable.
These genes were classified using the April's 2008 Gene Ontology classification [ 22] and found that 6 (YKL152C, YCR012W, YKL182W, YPL231W, YBR256W, YBR256W) out of these 18 unpredicted essential metabolic genes shared the same classification with predicted essential genes (see Additional File 2).
Kanuik wanted to be able to share in the same classification by choice, not because of family history.
To cover an as broad as possible range of gene-related information, we additionally investigated whether incorporating information on proteins belonging to the same protein family or sharing the same protein domain improves classification.
Each row-box shows the organisms sharing the same pathway and the corresponding classification.
We tested this hypothesis by comparing the expected and observed frequencies of neighboring colonies (those sharing the same pallet and those with entrances facing in the same direction) with the same or different classifications (dead, weak, or acceptable).
