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How are peroxisome retention and transport balanced to ensure equitable sharing of peroxisomes between mother cell and daughter cell?
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This information subsequently allowed unraveling of the principles of human peroxisome biogenesis disorders because of the strong conservation of the molecular mechanisms of peroxisome development between lower and higher eukaryotes.
Numerous reports demonstrate that Arabidopsis myosins of class XI share common functions, such as the transport of peroxisomes [ 18- 20, 47].
Furthermore, the shared loss of functional fatty acid biosynthesis pathways and the absence of peroxisomes, the latter organelles presumed ubiquitous in eukaryotes except for parasitic protozoans, were inferred.
Still, how may interactions between only a subpopulation of peroxisomes potentially contribute to peroxisome dynamics?
Yet, no direct evidence of physical contact in vivo between mitochondria and morphogenesis of peroxisomes is available, except for genetically modified cells cultured in vitro.
Despite the evident importance of peroxisomes in brain development and function, the relationship between peroxisomes and neurological dysfunction is far from clear.
Our initial experiments do not support the exchange of protein markers, but a close apposition of peroxisomes might favor an exchange of certain metabolites between heterogeneous organelles.
fNumber of shared polymorphic sites between species.
The relative distribution of puncta between mother and bud is a measure for segregation of peroxisomes during cell division.
Although the reason for the loss of peroxisomes from O. dioica is unclear, organisms lacking peroxisomes, including the free-living O. dioica, share certain typical r-selected traits: high fecundity, limited ontogenesis and relatively low complexity of the gene content.
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