The present study aimed to understand if patients with LOA shared clinical features, risk factors and co-morbidities with EOA.
As they share clinical features with other pathogens, the initial spread of these viruses can be misdiagnosed.
Scrivener Y et al. concluded that 4 (7 %) of the 62 patients with LS shared clinical features on the cheek and/or mentum [9].
Different pain syndromes of unknown aetiology often share clinical features [4, 5] and several studies indicate that FMS and TTH have several common features, both with regard to pathophysiology, demographics and clinical symptoms, though there are also clear differences between the two conditions [6, 7].
With few exceptions, the current stage of medical practice emphasizes disease classification based on shared clinical features which together are representative of a syndrome.
They share clinical features including fever, arthralgia, respiratory distress, renal dysfunction, and neurologic disorders; but their course and prognosis are heterogeneous.
Mutations in RECQL4 are associated with RTS, BGS and RAPA, which share clinical features, including short stature, skeletal abnormalities and radial ray defects.
The rare hepatoid carcinoma of the biliary tree may mimic Klatskin-type cholangiocarcinoma with its shared clinical features such as old age, anatomic location, and aggressive behavior.
42 In our study we delineated an expanded phenotype of degenerative disease based on shared clinical features and de novo mutations of KIF1A.
Molecular diagnostics can resolve locus heterogeneity underlying clinical phenotypes that may otherwise be co-assigned as a specific syndrome based on shared clinical features, and can associate phenotypically diverse diseases to a single locus through allelic affinity.
