However, both histone reactive and healthy sera shared this reactivity pattern and thus were not determined to be significant by SAM.
For instance, non-addressed allele HLA-A*6801 HLA-A*6801 reactivity with A*6802 in reactionsharedA 002, 004, and 018 butheiffereactivityhe latter in having additional reactivity at reaction 017 and the absence of reactivity at 011.
First, there were the non- addressed alleles that fully shared a reactivity pattern with addressed alleles.
In the case of HLA-B, due to the allele complexity of the locus, 273/276 distinct patterns were attained, as the following pairs of addressed genotypes shared common reactivity patterns: B*4201/B*4202 and B*4201/B*4201; B*0702/B*4202 and B*0702/B*4201; and B*4201/B*8101 and B*4202/B*8101.
SEB and its close sequence relatives, SECs 1-3, shareactivityity with T cells bearing members of the mouse Vβ 3, 7 and 8.1-3 family [6] [7].
Before 1991, the Uukuniemi-like viruses were in a separate genus (Uukuvirus), but the similar molecular biological characteristics along with some weak serological cross reactivity shared with viruses in the Phlebovirus genus resulted in their reclassification [ 4].
Regarding the IgM network (whose topology does change from birth to adulthood), the retained centrality suggest that there exist a core of central IgM reactivities shared by both newborns and mothers, despite the differences in the immune network overall architectures.
Note that both the CST and the anti-idiotypic network paradigms [40], [41] are based on individual differences between the immune repertoires developed by individual subjects; the immunological homunculus idea, in contrast, highlights the existence of antigen reactivities shared by individuals within a population.
Results demonstrated that the two sdAbs were specific for serotype O and shared no cross-reactivity with serotypes A and Asia 1.
