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Deckner et al. (2006) operationally define child interest as the duration of engagement and participation by the child during shared interactions between the parent and the child.
In this section we quantified the extend of local and globally shared interactions between the inferred GRNs and ppi networks.
Thus, the interaction overlap is defined as the average percentage of shared interactions between common proteins [ 12].
Aggregation of conditions within families can also reflect a shared environment or shared interactions between genes and environment.
Another uses pathway pair scoring, comparing not only the overlap of the resultant genes, but also weighting by shared interactions between the pathways.
The intersection of two nodes is all shared interactions between the two nodes, with the union of the two nodes being all the nodes that interact with at least one of the nodes of interest.
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Exceptions are two interactions affecting humerus and femur and two interactions affecting ulna and tibia (supplementary table S2, Supplementary Material online); however, the effect size or the pattern of shared interactions differ between traits (i.e., whether additive × additive, additive × dominance, etc., interaction is significant [ Routman and Cheverud 1997]).
HeLa nuclear extract (lane 3) shared interactions at approximately 92 and between 33 and 32 kDa, with fainter bands at 64, 60, 51, 39, and 23 kDa.
The Simpson index captures the proportion of shared interaction partners between each gene pair, relative to the degree of the least-connected gene [ 16].
This coupled with a shared interaction of CCL2 between tuberculosis and azithromycin promotes that idea that azithromycin may have a therapeutic effect on tuberculosis through an anti-inflammatory response.
The last model also included interaction terms between country and all fixed factors in order to analyze the country specific role of family structure and family wealth on shared activities (interactions between covariates are excluded by sampling procedures).
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