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Inversions had to share the same direction and 50% or more identity to be classified as shared.
Nevertheless, the observed statistical heterogeneity was more quantitative than qualitative because all estimates for study designs share the same direction.
how often is only one of the two alleles expressed? is there a genome wide bias towards expression of the paternal or maternal allele; and finally do genes that are nearby on a chromosome share the same direction of ASE?
For instance, to what extent is ASE tissue specific; how often does the direction of imbalance reverse between tissues; how often is only one of the two alleles expressed (mono-allelic expression or MAE); is there a bias towards expression of the paternal or maternal allele; and do genes that are nearby on a chromosome share the same direction of ASE?
Similar(56)
Moreover, we observed a correlation of 0.58 between the effect sizes of the interactions in both datasets (p-value = 5.9 × 10−24), with 202 of the 246 interactions sharing the same direction of effect (p-value = 2.2 × 10−25).
Genes expressed differentially between early stages, as between both C-I and C-II and L-I and L-II also overlapped significantly and over 95%% of these genes shared the same direction of change, which likewise implies a shared mechanism for early growth and developmental patterning common to both tissue types.
If the recorded neurons shared the same direction preferences and had either overlapping or colinear RFs, correlated activity was present for both the coherent and the noncoherent motion of the stimulus, indicating that the neuronal responses were associated to the contours of only one of the components.
Genes expressed in both leaf and cotyledon tissues, and which demonstrated significant differential expression between both C-II and C-III and L-III and L-IV (genes that change in expression in anticipation of tissue senescence in both organs) were shown to have a significant overlap, and 99.0 % of these genes shared the same direction of change (up- or down-regulation) in both tissues.
We found that the majority of eQTLs are shared and that an absolute majority of shared eQTLs has the same direction of effect in different tissues, meaning that if a given allele increases the expression of the gene in blood, it also will increase the expression of the same gene in lung.
If two seeds are correlated with their shared features in the same direction, F=1 (seeds are fully concordant); if they are correlated with their shared features in opposite direction, F=−1.
Proteins sharing miRNAs in the same direction among the functionally validated miRNA-protein associations were in most cases found to be clustering together in the interactome heatmap.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com