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Even low-resolution genotyping can guide sequencing for this purpose by identifying a subset of cases who share markers with an affected relative.
According to the recent publication of Dresing et al. [29], TNF-α and iNOS producing Tip-DCs, that share markers with macrophages, were the main cellular source of IFN-β in the course of Listeria infection.
Each subset is a window and windows can share markers.
For example, EPCs share markers of both stem and mature endothelial lineages [ 56].
However, the precision of these methods may be low because species may contain multiple markers and different species may share markers (Case et al., 2007).
Linkage analysis resulted in assignment of 335 loci to 34 linkage groups (Table S2, Table S3, Table S4, and Table S5), although one linkage group (Ck33) was not mapped in the male parent, and another (Ck31) did not share markers between the sexes.
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This level of relatedness makes is likely that Holiday and Korona share marker haplotypes that are identical by descent.
Three gene finding studies showed that gay brothers share genetic markers on the X chromosome; the most recent study also found shared markers on chromosome 8.
This process can be repeated iteratively until the number of shared markers between the two sets is maximized.
In contrast to shared markers, the markers found to be exclusive to HVC may reflect functional properties unique to HVC.
Shared markers between candidate CSC and stem cells also include pathways that mediate cell self-renewal and pluripotency.
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