Exact(11)
Upon binding their distinct ligands, Nod1 and Nod2 share downstream signaling through Rip2-TAK1 to activate NF-κB transcription activity (Caruso et al., 2014).
The fibroblast growth factor (FGF) receptor is also proposed to share downstream signaling pathways with CAMs during the stimulation of neurite growth (Kolkova et al., 2000).
However, it has been suggested that Stat3 and c-Myc share downstream targets.
Prostasin and PSP94 have similar roles in chemoresistance in ovarian cancer and share downstream targets.
From their studies, these investigators suggest that these two oncogenes share downstream targets and induce cell transformation through similar genes.
Like transcripts with alternative unique first exons, such nested transcripts again share downstream exons and the termination codon.
Similar(49)
It makes commercial sense for Russia to look for new customers in China, Japan and India, as well as to seek to buy shares "downstream" in energy distribution companies in Britain and other European states.
This shared downstream output of the deregulated Hippo pathway provides attractive therapeutic targets that may have the potential to treat patients that exhibit a variety of molecular alterations that feed into the Hippo pathway.
NOTCH and TLX1 may synergistically cooperate to regulate shared downstream target genes [37].
This emphasizes the complexity of the crosstalk and suggests that it may not simply be a matter of shared downstream targets of the pathways.
In the soma the maternally inherited unmethylated allele binds CTCF at four sites in vivo [26], [31], [32], [33], [34], resulting in insulation [34], [35], [36], [37], [38], [39] between the insulin-like growth factor 2 (Igf2) promoters and the shared downstream enhancers [40].
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