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Minicollagens share common domain architectures with a central collagen sequence flanked by polyproline stretches and short N- and C-terminal CRDs.
In particular, we introduced the concept of "domain clubs", which are sets of proteins that share common domain compositions.
11 These members all share common domain structures, including N-terminal HEAT Huntingtin, elongation factor 3, protein phosphatase 2A, and yeast kinase TOR 2 (HEAT) repeats, a FRAP, ATM, TRRAP (FAT) domain, a protein kinase domain, and a C-terminal FAT-C domain.
Paraspeckles are one of the most recently identified nuclear bodies and contain a family of RNA-binding proteins called the DBHS (Drosophila behavior and human splicing) family proteins, which share common domain structures consisting of three RNA recognition motifs arranged in tandem (Fox et al., 2002; Bond and Fox, 2009).
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To subclone, cDNA from the first instar larvae was used as a template to obtain a 527-bp PCR fragment of the shared common domain, and two full-length cDNAs were obtained with a combination of 3'-RACE and 5'-RACE methodologies.
Proteins belonging to different families, but sharing common domains, may thus have escaped detection.
Protein kinases share common catalytic domain structures composed of a small N-terminal lobe and a large C-terminal lobe.
Ror RTKs share a common domain structure.
Both proteins share a common domain architecture with hydrophilic N-terminal and hydrophobic C-terminal regions.
These proteins share a common domain architecture and promote bacterial adhesion to host cells.
RbSTAT1 and RbSTAT1L were found to share a common domain architecture with mammalian STAT1.
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