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The primary function shaping the sequence of an SS is spliceosomal recognition.
We comprehensively investigated the nucleotide diversity and haplotype structure and examined the possible role of natural selection in shaping the sequence variation throughout the gene cluster.
Thus both phylogenetic analysis and examination of the evolutionary forces shaping the sequence of R2GHs support the existence of two distinct modes of evolution acting in R-gene homologs from different lineages.
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Our results reveal how a chaperone can shape the sequence landscape at both the protein and RNA levels to harmonize competing constraints posed by protein stability, aggregation propensity, and translation rate on successful protein biogenesis.
Another six respondents reported that textbooks helped shape the sequence and content of their courses.
Because of the complexity of the NAD metabolic network (Fig. 1) it is difficult to make clear predictions on how evolutionary forces have shaped the sequence composition of NAD metabolic enzymes.
Clearly, a comprehensive mapping of the chemical space of α-hydroxy acid-catalyzed peptide formation will require a systematic investigation and substantial effort, and doing so may provide valuable clues regarding the chemical pressures that shaped the sequences and structures of peptides formed on the prebiotic Earth.
The data argue that selective pressure against protein aggregation plays an important role in shaping the protein sequence space.
Identifying features shaping the architecture of sequence variations is important for understanding genome evolution and mapping disease loci.
Identifying features shaping the architecture of sequence variations is important for understanding genome evolution and mapping of disease loci.
The average-sized but repeat- and feature-poor mitochondrial genome of Vigna makes it ever more difficult to generalize about the factors shaping the size and sequence content of plant mitochondrial genomes.
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