Based on the pooled treatment effects regarding the scale and shape of each intervention relative to DTIC (d0 Ak, and d1 Ak, with k = B,C,D, corresponding to respectively DTIC + IFN, DTIC + non-IFN and non-DTIC) the resultant HRs as a function of time were obtained according to ln(HR Ak ) = d0 Ak + d1 Ak · ln(t).
Was the shape of the intervention effect prespecified?
The concrete shape of the intervention was developed and performed by the Vietnamese collaborators.
Although existing studies have pointed out that political opportunities play a significant role in the success of protests in China (e.g. Cai 2010), they mainly emphasize the importance of direct intervention from higher-level governments and have not differentiated modes of government intervention nor elaborated how different modes of intervention shape protest success.
"As far as recent statements by government officials are concerned, it is also wrong to speculate on the shape of future E.C.B. interventions," the bank said.
Foreign policy has always had a masculinity issue: gender shapes war, gender shapes intervention and gender shapes peacekeeping.
It is argued that home energy improvement are complex interventions and that a better understanding of the latent mechanisms and contextual issues that may shape the outcome of interventions is needed for effective intervention design.
Firstly, productive power defines what is considered as a problem; it shapes reality and provides areas of intervention where actors are obliged to act in order to fix the problem for instance, the need to protect COTM.
We view caregiver capabilities as an effect modifier of intervention impact, potentially shaping the heterogeneity of the effects of the interventions.
13 14 In terms of intervention design, the broad shape of the DQIP intervention was defined by the intention that there should be evidence for the effectiveness of its components, that it should be built on existing National Health Service (NHS) information technology and be implementable as an 'enhanced service' (a UK National Health Service mechanism for commissioning general practice care).
It is likely that knowledge of timing constraints on viral mutations could shape preventive and therapeutic strategies by identifying optimal times of intervention.
