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The coexistence of "normal" and elongated carboxysomes in mutant cells and among the population of purified mutant carboxysomes was unexpected and indicated that, contrary to the prediction of the current shell model [10], the two CsoS4 proteins are not essential shape determinants in the shell of α-carboxysomes.
Microstructural shape determinants such as elongation of cells and voids and anisotropy of the tissue are correlated to each other, but mostly uncorrelated to other microstructural descriptors and functional properties.
Bacterial two-hybrid analyses and pull-down experiments showed that MreC interacts with the penicillin-binding proteins that synthesize the cell wall and therefore are cell shape determinants (Divakaruni et al, 2005, 2007; van den Ent et al, 2006).
Piet de Boer's group identified rodZ by screening for the requirement for extra FtsZ, as it was known that increased FtsZ levels rescue the lack of other cell shape determinants (i.e. MreB and PBP2) (Bendezu and de Boer, 2008).
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This parameter determines the shape of the washout curve, which is the predominant shape determinant of the GDC model.
Presents crescentin as a cell shape determinant in C. crescentus and as an intermediate filament-like protein.
FtsZ is essential for cell division, MreB is a rod shape determinant and crescentin is required for the curved-rod shape of Caulobacter crescentus.
While knockouts of cell shape determinant (csd) genes did not affect growth in vitro in that study, it still could prove important to investigate the effects of DFMO on peptidoglycan and associated csd genes in future experiments.
Our understanding of bacterial cell shape has taken steps forward with the recent discovery of cytoskeletal elements such as cell-shape determinants, but there is still much to learn about how shape is generated and maintained.
Limited to 15. Provides a critical introduction to the shape and determinants of political, social, and economic inequality in America.
Varley, A. W. & Stewart, G. C. The divIVB region of the Bacillus subtilis chromosome encodes homologs of Escherichia coli septum placement (minCD) and cell shape (mreBCD) determinants.
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