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Cell shape and tissue architecture are controlled by changes to junctional proteins and the cytoskeleton.
Since DE-Cadherin is enriched at Adherens Junctions (AJ) in the apical region of cells, it was also used to follow apical cell shape and tissue dynamics.
The depth limits with TPSM are in the range of 600 800 µm depending on various factors such a wavelength, laser pulse shape and tissue properties [68].
Light microscopic examination revealed that the sensory hair cells in all of the vestibular regions (ampullary cristae and saccular and utricular maculae) appeared normal with regard to their number, shape, and tissue architecture (Fig. S3C, D).
Despite the two lineages (the C. clussi and the C. salviifolius groups) are inhabiting the Mediterranean basin, the C. salviifolius group has undergone higher differentiation and displays greater variation in leaf trichome density, size, shape and tissue thickness than do the C. clusii group.
10.7554/eLife.03270.007 Figure 2. Dnhe2 over-expression disrupts cell shape and tissue organization and increases proliferation.
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These discrepancies between cell shape changes and tissue shape changes require topological changes in the cell network.
GMR > Dnhe2 pupal eyes had severely disrupted cell shapes and tissue organization, and ommatidia overall were smaller than in wild type.
Here, we have identified a novel mechanism in which canonical Wnt signalling controls laminin synthesis to regulate epithelial cell shapes and tissue morphology during vertebrate appendage development (Fig. 8G).
Understanding this tool is an important prerequisite for our comprehension of cellular force response, cell shape dynamics, and tissue organization.
Msn is a MAPK kinase kinase kinase (MAPKKKK) within the JNK signaling cascade, a pathway known to function in lamellocyte production [13] and in cell migration, cytoskeleton rearrangement and cell shape change, and tissue morphogenesis [19].
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