Appalled by the shallow response, Shaw stormed off.
Run above Flash Gordon, Raymond's Jungle Jim is described by Armando Mendez as "a thing of beauty... always more than just a topper or a shallow response to Hal Foster's exquisite Tarzan".
In a condescending but shallow response to a Huffington Post piece written last week by my colleague Emily Phelps and me, Wall Street Journal columnist James Taranto accuses us of appealing to "emotion" and wallowing in "nostalgia for the heroism of the civil rights movement half a century ago".
Comparison between the 7-substituted branched 8HQ described in Smirnova et al. and the present qHTS dataset reveals one direct structural match, SID 14737227: this compound displayed a shallow response and relatively weak potency against JMJD2E (IC50 of 39 µM, Table S1).
That is, the anticooperativity of α-ketoglutarate binding provides a shallow response to physiological concentrations of α-ketoglutarate, a desirable feature for an accurate biological sensor.
Shallow, red-top-style headlines only reinforce shallower responses to a profoundly tragic set of circumstances.
In contrast, the slower pathway registers a more prolonged but shallower response.
A steep decline in EPC levels was observed within 4 days of CAP exposure (33% decrease; p < 0.05); whereas longer exposures were associated with a shallower response.
Importantly, these shallow dose responses provide evidence against a non-specific mechanism of inhibition involving colloidal CLR01 aggregates, as aggregating inhibitors tend to exhibit steep dose response curves (Shoichet, 2006).
We proposed a simple method to correct differential P-wave travel times between two sites for shallow-layer reverberation by cross-convolution of the shallow-layer responses at the two sites.
