Sentence examples for sexual defects from inspiring English sources

Downregulation of either pro11 in ∆Smmob3, or Smmob3 in pro11 mutants by means of RNA interference (RNAi) resulted in synthetic sexual defects, demonstrating for the first time the importance of a putative PRO11/SmMOB3 complex in fruiting body development.

Interestingly, despite the lower strength of MSUD suppression, dramatic sexual defects were observed in heterozygous sad-3Δ × sad-3+ crosses, an observation unique among all reported MSUD genes to date.

The other four GPCR mutants with sexual defects (Δ gpr-1, Δ gpr-2, Δ gpr-3, and Δ gpr-15) all exhibited phenotypes in the perithecial phase, with Δ gpr-15 having both a protoperithecial and perithecial defect.

However, it is should be noted that the sexual defects of these mutants are mating-type dependent; Δ pre-2 is only female-sterile in mat a, and Δ pre-1 in mat A (Kim and Borkovich 2004; Kim et al. 2012) (Table 1).

"It's one more step in the evolution of vibrators to just another consumer product, unburdened of its freight of shame, sexual defect and sluttiness".

In our previous study of N. crassa kinases (Park et al. 2011b), we found that 32 out of 77 (42%) mutant strains exhibited defects in sexual development, with 30 out of 77 (39%) unable to produce ascospores (female-sterile; 94% of sexual phenotypes).

The Δpde1 mutant displayed certain defects in sexual differentiation and several important characteristics of virulence, and, moreover, the Pde1 activity is regulated through PKA-derived phosphorylation [26].

ATR has been associated with defects in sexual development in animals, but studies on mammalian systems have failed to clearly identify a cellular target.

Most of the 15 mutants that had phenotypes in sexual development also exhibited defects in basal hyphae extension and asexual differentiation.

Of these deletion mutants, three showed defects in sexual development in N. crassa, and 12 in F. graminearum (Additional file 1 Table S1).

Importantly, although Δ gpr-15 and Δ gpr-29 mutants both have reduced linear growth rates, Δ gpr-15 uniquely possesses defects in sexual development and Δ gpr-29 in aerial hyphae extension (Table 1).