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The sex specific effect in weight shown here may be related to testosterone levels, since a strong correlation between body mass and testosterone levels is known to exist.
It was hypothesized that a sex specific effect at eae 13 might be responsive to testosterone levels and, thereby, give males a greater ability to control disease once it is initiated.
Although this finding may seem to refute our conclusion of a sex specific effect on recurrence, the interpretation of findings in this subgroup of patients is limited because the number of patients studied was smaller and patients with provoked venous thromboembolism have a low risk of recurrence.
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Somewhat lower within pair correlations for the opposite sexed twins than for the like-sexed DZ twins suggest a sex-specific effect, i.e. that different genes or shared environments are operating in men and women.
Lower within pair correlations for the opposite sexed twins than for the like-sexed DZ twins suggest a sex-specific effect, i.e. that different genes or shared environments are operating in men and women.
The study is "the first to identify a specific sex chromosome gene that has a sex-specific effect on the brain," says UCLA neuroendocrinologist Arthur Arnold (who was not involved in the study).
As sex may contribute to the genetic predisposition [14], [18], sex-specific effect of chromosome 9p21 was also tested.
Interestingly we also noted a strong sex-specific effect in the dexamethasone study consistent with our previous findings [24].
For grip strength and walking speed, the sex-specific effect estimates were standardised by dividing the coefficients by the standard deviations (SDs).
Here we report a sex-specific effect of the Hp haplotype E (-101G, -61A, Hp1) and susceptibility to active trachoma in Gambian children.
To examine the sex-specific effect, we further elucidated the above significant associations of candidate SNPs and atherosclerosis phenotypes by sex stratification.
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