Some sporadic transgenic mice with low phenotype severity appeared to develop normal hair coat, showing several spots in which hair was absent.
Our data reveal that levels of OAC measured on admission allow for discriminating the different degrees of severity to be developed on the progression of the disease in the long run, which should have a direct impact on the clinical management of these patients.
The goal is to develop "severity measures within each diagnosis," said Dr. Darrel A. Regier, research director at the American Psychiatric Association and vice chairman of the diagnostic manual's task force.
The method uses gradient analysis (ordination method of Canonical Correspondence Analysis) for assessing the weights of Ns descriptors' effects, which are further used to develop weighted severity indices; the severity index of WQ (Swq) and Es invasion (Se), respectively.
The only other study that attempted to develop a severity model also used a patient-reported outcome, global VAS, as the anchor for FM severity [ 20].
Although control of the abnormal metabolic state associated with both types of diabetes has a major impact on the incidence and severity of nephropathy, the propensity to develop this complication is, in part, genetically determined [4], [5].
This commentary discusses recent attempts to develop useful severity criteria to guide the use of ICU resources in patients with severe CAP.
Female 'Rescue' mice were similarly generated by tamoxifen administration, but injection times ranged from 270 to 320 days of age to allow similar levels of phenotypic severity in the female mice to develop.
Yet considering the length of similar sequence at the 3' end and the hyper variable region at the 5' end, we conclude the hypothesis may not completely explain the course of disease severity and emphasize the need to develop superior biomarkers to predict the course of the disease.
For example, it doesn't take much weight gain for Asians to develop the same severity of sleep apnea compared to those of Caucasian descent.
