Sentence examples for severity of the target from inspiring English sources

Motola et al 13 considered all drugs approved by the European Medicines Agency (EMA) between 1995 and 2003 according to an algorithm that considered the severity of the target indication, availability of existing treatments and size of therapeutic benefit.

A priori defined subgroup (in case of categorical predictors) or meta-regression (in case of metric predictors) analyses will be performed according to the subtype of chronic depression, duration (onset) and severity of the target disorder, as well as study quality.

Also, the severity level of the target route can be determined using zonation criteria in real time.

First, as already mentioned, physicians were asked to rate severity of the patients' target disease whereas patients provided global rating of their overall health.

The spectrum of patients refers not only to the severity of the underlying target condition, but also to demographic features and to the presence of differential diagnosis and/or co-morbidity.

A second limitation may be the generalizability of the study, which may be limited due to the variability of the predicting factors, prevalence of TB severity, and spectrum of the target population.

Qualitative safety targets are those where the occurrence of systematic failures are minimized by applying a variety of defenses and design disciplines appropriate to the severity of the tolerable risk target.

Nine themes that reflect the attitudes of Dutch GPs were identified: prevention and the influenza vaccination programme; usefulness of additional vaccines; evidence-based practice; severity of the infectious disease; target population; participating organizations; potential barriers; and autonomy.

The severity of NOTCH3 target genes deregulation in the parents seems to reflect the relative fold change of wild-type NOTCH3 itself, which was found to be higher in the father than in the mother.

Along this line, patients were also asked to rate the severity of their target disorder in terms of the impact on five salient activities, and this measure was associated with physician-estimated disease severity (Table 4).

One reason for the weak associations between physician and patient global ratings may be that physicians were asked to estimate the severity of a single target condition rather than the patient's overall health.