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When the severity of restriction was increased, but the duration held constant and the reserves were more depleted, there was a greater PRH response.
In these studies, both of which were performed in the lab, the authors found that the likelihood of observing a SRE was proportional to the severity of restriction of primary reproduction.
The sustained hunger neuropeptide profile during restriction, combined with the data on extent and severity of restriction (experiments one and two) on the PRH response suggested that a peripherally generated signal, produced either by the depleted fat or lean tissue, was stimulating appetite and generating the PRH (Dulloo et al., 1997).
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Nowadays, there is no real market, such is the severity of restrictions in force.
Our findings of increased infant mortality among SGA infants are consistent with another African study (Kasirye-Bainda and Musoke, 1992), with the risk increasing with severity of growth restriction, such that severely SGA infants had a 3-fold significantly increased hazard of death before and after adjusting for other confounders.
Kramer et al. (1989) showed that disproportionality increased with increasing severity of growth restriction, suggesting the presence of a continuum of fetal growth restriction, rather than two distinct patterns.
10 Several studies have demonstrated that both behavioural and neurological deficits correlate with severity of growth restriction.
We sought to evaluate the impact of severity of growth restriction on mortality and major neonatal morbidity among very-low-birthweight small-for-gestational-age infants.
37 The extent of astrogliosis was correlated with the severity of growth restriction.
The severity of flow restriction caused by an arterial stenosis can be accurately assessed by this most comprehensive noninvasive method (Kohler et al 1987).
The perinatal outcome of IUGR fetuses is largely dependent on the severity of growth restriction with those below the 3rd centile and/ or abnormal umbilical artery Doppler measurements at greatest risk of adverse outcome [ 1].
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