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While a number of studies have compared different strains of mice, and looked at multiple parameters for severity of response (e.g. in [33]), this is usually done using the Ovalbumin model of allergic airway inflammation, which makes it difficult to examine dose responses.
There is also variability in nature and severity of response to a given dose of a particular food allergen.
However, the severity of response at these levels is generally mild, and only a small portion of the population may respond".
The pathway of key biological events occurring between food intake and allergic response is considered, along with factors that may determine the nature and severity of response to food allergens.
In addition to the location of mediator-tissue interactions, variables related to the specific type of mediator and specific receptor polymorphisms may affect the nature or severity of response.
It is, therefore, reasonable to postulate that genetic variation contributes to determining the severity of response by irradiated tissues in the body and that this variation is reflected in gene expression patterns.
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Such an analysis helps to generate a coherent picture of the various "drivers" of the allergic response, including drivers that determine the nature or severity of the response.
Host specific factors associated with the severity of this response include mechanical and immunologic factors such as an imbalance between Th1 and Th2 type responses [37], [38].
Serum albumin levels fall as part of the acute phase response to inflammation, and its association with mortality may reflect a role as a marker of severity of host response to the surgical insult.
"Even if the three arrested women did take part in the protest," Amnesty said on Thursday, "the severity of the response of the Russian authorities – the detention on the serious criminal charge of hooliganism – would not be a justifiable response to the peaceful – if, to many, offensive – expression of their political beliefs.
Many Chileans have bristled at the severity of the response by the authorities here, who twice sent Mr. Kahn to jail after invoking a seldom used antiterrorism law.
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