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In the lightening of these findings, we concluded that oxidative stress may have a critical role in hepatic injury and is associated with the severity of disease and the replication status of virus in hepatitis B infection.
Oxidative stress occurs secondarily to increased total lipid peroxidation and inadequate total antioxidant response and is related to severity of the disease and replication status of virus in hepatitis B infection.
Apart from direct tissue damage resulting from EBOV replication, the severity of EBOV disease also results from indirect effects of virus replication, such as the induction of proinflammatory cytokines, depletion of T lymphocytes and coagulation abnormalities.
The primary goal in treatment of influenza infection is to relieve symptoms and limit the severity of infection by inhibiting virus replication.
Complex and incompletely understood patterns of replication of mitochondria in the developing embryo mean that it is rarely possible to predict accurately the severity of mitochondrial diseases.
This is the first study to demonstrate that non-specific stimulation of the immune system by a vaccine or an immuno-modulator drug can potentiate viral replication and increase the severity of clinical signs during an outbreak of PMWS.
ESR1 and ESR2 polymorphisms were suggested to present association with predisposition to and severity of IS [ 22, 23], however two replication studies did not confirm these findings [ 24– 26].
This allowed yet another layer of replication.
Hence the difficulty of replication.
How about extending the notion of replication?
Here are eight innovations worthy of replication.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com