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In these studies, we showed that individual mutations exhibited phenotypes that were not, with respect to the severity of interference, predictable by our current knowledge of the structural design of IF proteins.
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This is consistent with our theoretical predictions in that the severity of the interference would increase in the presence of such diversity because the cumulative effect of all the interferences emerging from the various transmitting channels.
Finally, "severity of the interference figures in the calculus as well".
Specifically, the constitutionality of a seizure turns upon "a weighing of the gravity of the public concerns served by the seizure, the degree to which the seizure advances the public interest, and the severity of the interference with individual liberty"...
The secondary efficacy end points were the severity of symptoms, interference with daily life, and level of pain.
The severity of the interference depends mainly on two factors namely the number of pulses and the amplitude intensity of the flash.
The scale consists of five questions about frequency of anxiety, severity of anxiety, avoidance, interference with tasks and interference of social relationships.
This 16-item scale measures four dimensions of fatigue: severity, distress, degree of interference in activities of daily living, and timing.
The 16-item Multidimensional Assessment of Fatigue (MAF) measures four dimensions: severity, distress, degree of interference in activities of daily living, and timing.
PRO-CTCAE symptom attributes include frequency (F) (e.g., "In the last 7 days, how often did you have nausea?"), severity (S) (e.g., "In the last 7 days, what was the severity of your pain?"), interference with daily activities (I) (e.g., "How much did fatigue interfere with your usual or daily activities?"), and presence/absence/amount (P) (e.g., "In the last 7 days, did you have any bed sores?").
Quantifies the symptoms of orthostatic intolerance due to hypotension, with questions related to frequency and severity of symptoms and interference with daily activities.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com