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The comparative study of several rudiments shows an intriguing correlation between severity of effect and position of the rudiment on the anteroposterior axis (forelimb vs. hindlimb) and proximodistal axis.
Table 2 Severity ratings for a failure in railway rolling stock Rating Effect Criteria Severity of effect 1 None No disruption No effect 2 Very minor Minor disruption to rail services An inspection is carried out.
The fundamental principle in regulatory toxicology is that all chemicals are toxic and that the severity of effect is proportional to the exposure level.
Quantitation has usually been in the form of percentages of embryos affected, but when severity of effect is indexed, more critical analysis is allowed.
Categories are loosely ordered by the severity of effect, with LoF annotations listed before nonsynonymous, synonymous, non-exonic categories and so on.
On the other hand, there is abundant evidence of deleterious mutations, varying in severity of effect from strongly deleterious to very mild, particularly in regions conserved in the outgroup taxa, indicating a history of persistent purifying selection.
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The EX distance is based on experimental assays of the severity-of-effect of amino acid substitutions on protein function and was specifically designed to reflect functional differences in amino acid sequences while being free of mutational bias.
The WoE approach means that all available information is assessed through expert judgement for its suitability and reliability, and relative weights are assigned (e.g. quality of the data, consistency of results and/or data, nature and severity of effects, relevance of the information for the given regulatory endpoint).
The severity of effects can go from 0-10 very quickly".
The severity of effects can go from zero to ten very quickly".
The severity of effects differs depending on the particular scenario, but the undeniable fact is that nuclear war poses a grave and present danger to our planet.
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