Because of the observed relationship between severity of symptoms and differential expression of candidate genes across the 5 autistic twin pairs studied, SAM was applied to microarray data from all 5 sets of twins to identify genes that were significantly up- or down-regulated across all twin pairs, each pair of which exhibited differential severity with respect to language ability (Table 5).
Eyes of aged, targeted replacement mice expressing human apoE2, apoE3, or apoE4 and maintained on a HF-C diet show apoE isoform-dependent pathologies of differential severity.
The differential severity of the pandemic in these regions may be explained partly by differential transmissibility.
The differential severity of the pandemic in these regions may be explained partly by differential transmissibility, and suggests the need for more nuanced, targeted or population-specific control strategies in Canada.
Specifically, the results show that the differential gene expression profiles of concordantly autistic twins with differential severity of language impairment mirror some of the differences in gene expression which are observed in the twins with discordant diagnosis of autism, who also exhibit differential language deficits.
Does catastrophizing influences one's subsequent pain responses or do individual differences in the perceived severity of pain lead to differential rates of catastrophizing?
Why we observe an association of the Arg/Arg genotype with outcomes among black but not white beta-agonist users is unclear and could be due to differential severity of respiratory disease, underlying differences in response to beta-agonist medication, or chance.
Epidemiological data indicates that approximately 26-30% of diabetic patients suffer from differential severity of depression, excessive above that of the normal population [ 3, 4].
We were unable to adjust for differential severity of disease state in patients since to gain sufficient patient numbers we matched on the reason for the consultation using just the first three digits of the ICD-9 code.
Moreover, different subsets of touch neurons also display differential severity of morphological defects, and even vary in the type of defects that can be observed., It is intriguing that this kind of aging heterogeneity exists even between neurons of the same type.
